Tag Archives: GCB 2015

Poster at GCB 2015 on mutational landscapes of relapsing neuroblastoma

Bioinformatics Analysis of Heterogenous Data Reveals Characteristic Mutational Landscapes of Neuroblastoma Relapses, GCB 2015 in Dortmund

Marc Schunb-posterlte, Johannes Köster, Daniela Beisser, Corinna Ernst, Christopher Schröder, Alexander Schramm and Sven Rahmann

Neuroblastoma is a malignancy of the developing sympathic nervous system that causes 15% of childhood cancer-related mortality. However, in the vast majority of cases death results not from the initial disease manifestation but rather from metastasis or recurrence.

Systematic search for genomic alterations in primary neuroblastomas has shown low genetic complexity, with significant mutations in only a very few genes. This study explored the genomic landscape of relapsing neuroblastoma in order to evaluate ‘driver’ mutations to be exploited as therapeutic targets.

Poster about dinopy at GCB 2015

Henning Timm and Till Hartmann
dinopy
Dinopy (Dna INput and Output in PYthon) is a Python package that aims to simplify the development of bioinformatics applications by providing efficient facilities for DNA input and output.
At the time of writing, there is no library for I/O of DNA specific files available which makes full use of the potential of Cython. Dinopy exports Cython level API bindings which can be used by other Cython applications for increased speedup.